IGF-1 LR3 1mg
$59.95
IGF-1 LR3 is a synthetically modified, structurally enhanced analogue of mammalian insulin-like growth factor-1 consisting of 83 amino acids. It functions primarily as a highly potent agonist for the IGF-1 receptor (IGF-1R) in eukaryotic cells, playing a pivotal role in the activation of intracellular tyrosine kinase signaling pathways. In laboratory research settings, IGF-1 LR3 is a subject of intense investigation regarding its influence on cellular proliferation, hypertrophic signaling, and protein synthesis kinetics.
Scientific literature extensively explores the potential of IGF-1 LR3 to upregulate the PI3K/Akt pathway, stimulate myoblast proliferation, and inhibit cellular apoptosis. It is frequently utilized in experimental models focused on skeletal muscle hypertrophy, cellular differentiation, and tissue engineering longevity. By incorporating an N-terminal extension and a strategic amino acid substitution that severely reduces its affinity for inhibitory insulin-like growth factor-binding proteins (IGFBPs), IGF-1 LR3 is critical for understanding the mechanics of enhanced receptor bioavailability and metabolic signaling homeostasis in non-human biological systems.
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Features & Research Benefits
Our commitment to quality ensures that researchers receive a product capable of delivering accurate and consistent results.
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Exceeds 99% Purity: Analyzed via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry to ensure the removal of impurities and synthesis byproducts.
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Verified Structural Integrity: Precise amino acid sequencing ensures the peptide matches the exact chemical profile required for your research protocols.
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Stable Formulation: Supplied as a lyophilized white powder to ensure long-term stability and ease of reconstitution in laboratory solvents.
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Quality Assurance Guarantee: Every batch undergoes rigorous testing. We prioritize transparency and trust, providing researchers with reliable compounds for their data collection.
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Dedicated Support: Our team provides exceptional customer service to assist with technical inquiries regarding handling and storage.
Technical Specifications
For researchers requiring specific chemical data for their experimental design, the following specifications apply to IGF-1 LR3:
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Chemical Name: IGF-1 LR3 (Long Arginine 3 Insulin-like Growth Factor-1)
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Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
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Molecular Formula: C400H625N111O115S9
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Molecular Weight: 9111.6 g/mol
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Physical Appearance: White to off-white lyophilized powder
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Solubility: Soluble in water, 10mM acetic acid, or standard laboratory solvents
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Purity: ≥ 99.0% (HPLC)
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Storage: Store at -20°C. Desiccate and protect from light.
Compliance & Safety Disclaimer
CRITICAL WARNING: FOR RESEARCH USE ONLY.
This product is strictly intended for laboratory research and development purposes. It is not a drug, food, or cosmetic and is not approved for human consumption, veterinary use, or diagnostic procedures.
The chemical, physical, and toxicological properties of this material have not been fully investigated. It should be handled only by qualified individuals trained in laboratory procedures and familiar with the potential hazards of chemicals. All research must be conducted in compliance with applicable local, state, and federal regulations.
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